Recent information

A A
According to the „Journal of Clinical Investigation” the reason that causes multiple sclerosis (MS) to develop more frequently in females than males are brain differences between the two genders.
2014-05-19

According to the „Journal of Clinical Investigation” the reason that causes multiple sclerosis (MS) to develop more frequently in females than males are brain differences between the two genders.

There are 4 times more females with MS than males – up until now this difference was attributed to differences in hormone levels. However a new study conducted at the Washington University School of Medicine might suggest that the main culprit is S1PR2, a protein that is gradually deposited in the brain during the course of MS.

The research has shown that S1PR2 levels in the central nervous system are much higher in females than they are in males.

According to the scientists involved S1PR2 might be involved in forming the brain-blood barrier responsible for preventing harmful substances from entering the brain. Prof. Robyn Klein from the Washington School of Medicine stated that this finding might help in the development of new treatment methods for MS patients.


Share: